The effects of Fo Ti were first documented by Buddhist monks around 700 AD. From those times, within the context of traditional Chinese medicine, Fo ti (Ho-shou-wu) root has been used for hair loss, graying hair, fertility and as a tonic. More recently, scientific research suggests that Fo ti may increase the hair follicle growth phase (anagen phase), resulting in increased hair growth, and may prevent oxidative stress. Additional research also suggests that topical extracts of Fo ti  stimulate the cytokine Sonic Hedgehog (SHH) to promote hair growth.* ** ***

Used in: 

Evidence-Based Complementary and Alternative Medicine
Volume 2015 (2015), Article ID 517901, 10 pages

** Hair Growth Promotion Activity and Its Mechanism of Polygonum multiflorum. Yunfei Li, Mingnuan Han, Pei Lin, Yanran He, Jie Yu, and Ronghua Zhao

*** Polygonum multiflorum Radix extract protects human foreskin melanocytes from oxidative stress in vitro and potentiates hair follicle pigmentation ex vivo. Sextius P, et al. Int J Cosmet Sci, 2017